Hybrid plant MPC model including dynamic MPC sub-models

A method of generating a hybrid model predictive control (MPC) simulation model for a plant configured to run a process that processes at least one raw material to generate at least one tangible product. A predictive dynamic MPC sub-model is provided for each of plurality of process units in the plant, the plant including at least one process controller coupled to field devices coupled to the plurality of process units, where the process units comprise equipment for converting the raw material or an intermediate material formed from the raw material into to another material. A piping network diagram is obtained that provides a representation of a piping network for routing of the raw material and the intermediate material during the process. The dynamic MPC sub-models are coupled together using the piping network to generate the hybrid MPC simulation model which models the plant as a whole.