Platform agnostic query acceleration

Implementations described herein relate to systems and methods to provide platform agnostic query acceleration. In some implementations, a method includes receiving, at a processor associated with a query acceleration service, a request from an client/application, wherein the request conforms to a particular wire protocol of a plurality of supported wire protocols, and wherein the request includes header data and body content data, analyzing the request to identify at least one of a query and a command in the body content data, determining an optimal matched model of the one or more query acceleration models, rewriting the query based on the optimal matched model, transmitting the rewritten query to the query processing platform, receiving a response to the rewritten query or the query from the query processing platform, and transmitting the received response to the application, wherein the transmission is configured based on the particular wire protocol.