Compounds and pharmaceutical compositions thereof for the treatment of inflammatory disorders

The present invention discloses compounds according to Formula I:Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein.The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the sam...

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Hauptverfasser: Martina, Sébastien Laurent Xavier, Mammoliti, Oscar, Amantini, David, Coti, Ghjuvanni Petru Diunisu, Van Der Plas, Steven Emiel, Claes, Pieter Isabelle Roger, Annoot, Denis Maurice, Brys, Reginald Christophe Xavier, López Ramos, Miriam, Galien, René Alexandre
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention discloses compounds according to Formula I:Wherein R1, L1, R2, L2, R3, Cy, and the subscript n are as defined herein.The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of allergic diseases, inflammatory diseases, metabolic diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IFNα, IL12 and/or IL23 by administering the compound of the invention.