Compounds for the treatment of kinase-dependent disorders

Disclosed herein are compounds of formula I. Compounds of formula I inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of us...

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Bibliographische Detailangaben
Hauptverfasser: Wang, Yong, Bui, Minna, Xu, Wei, Jiang, Faming, Tso, Kin, Bannen, Lynne Canne
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed herein are compounds of formula I. Compounds of formula I inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.