Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules

Anti-betacellulin antibodies, fragments thereof, and multi-specific binding molecules

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BT...

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Bibliographische Detailangaben
Hauptverfasser: Ghosh, Joy Gispati, Etemad-Gilbertson, Bijan Alexandre, Bigelow, Chad Eric, Poor, Stephen Hedrick, Moker, Nina, Hanks, Shawn Michael, Chastain, James Edgar, Rangaswamy, Nalini Velamur, Toksoz, Engin, Qiu, Yubin, Twarog, Michael Zbigniew, Carrion, Ana Maria, Clark, Kirk Lee, Stefanidakis, Michael, Haubst, Nicole, Iyer, Ganesh Rajan, Nguyen, Andrew Anh
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety.