Modified guide RNAs

This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.

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Bibliographische Detailangaben
Hauptverfasser:	Morrissey, David V, Strapps, Walter, Smith, Amy Madison Rhoden
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	This disclosure relates to modified single and dual guide RNAs having improved in vitro and in vivo activity in gene editing methods.