Method and system for optical or electrical measurements in disperse fluids

The invention relates to a method of performing an optical or electrical measurement in a sample of a disperse fluid, the sample comprising particles and a fluid. The method comprises the steps of: a) positioning the sample in a microfluidic cavity having a resonance frequency, b) subjecting the sam...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jakobsson, Ola, Augustsson, Per, Blankenstein, Gert, Andersson, Klara, Schonbrun, Ethan, Kerimo, Josef, Ohlsson, Pelle Daniel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to a method of performing an optical or electrical measurement in a sample of a disperse fluid, the sample comprising particles and a fluid. The method comprises the steps of: a) positioning the sample in a microfluidic cavity having a resonance frequency, b) subjecting the sample, in the cavity, to an acoustic standing wave configured for causing the particles to congregate in at least one first region of the cavity, thereby causing the fluid to occupy at least one second region of the cavity, wherein the frequency of the acoustic standing wave is varied between a frequency below the resonance frequency and a frequency above the resonance frequency, and c) performing an optical or electrical measurement in the fluid in at least one of the at least one second region of the cavity. Varying the frequency ensures reproducible results. The invention also relates to a system therefore and a method and system for measuring hematocrit.