Tricyclic amine compounds as CDK2 inhibitors

Tricyclic amine compounds as CDK2 inhibitors

The present application provides tricyclic amine compounds, which are inhibitors of cyclin-dependent kinase 2 (CDK2), of Formula (I):as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.

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Bibliographische Detailangaben
Hauptverfasser: Ye, Qinda, Yao, Wenqing, Mukai, Ken, Wu, Liangxing
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present application provides tricyclic amine compounds, which are inhibitors of cyclin-dependent kinase 2 (CDK2), of Formula (I):as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.