TIGIT antibodies, encoding nucleic acids and methods of using said antibodies in vivo

The present invention relates to antibodies specific for one or more antigens, bispecific antibodies containing one or more domains with specificity to the target(s), and to immunocytokines. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the...

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Hauptverfasser: Arkinstall, Stephen John, Gillies, Stephen Douglas, Campbell, Jamie Ian, Ali, Mohammed Hanif, Sainson, Richard Charles Alfred, Carvalho, Joana de Abreu, Van Krinks, Cassandra, Sandy, Nikole, Germaschewski, Volker, Lee, E-Chiang, Kirby, Ian, Gallagher, Thomas, Kimber, Rachael Jane, McCourt, Matthew John, Kosmac, Miha
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creator Arkinstall, Stephen John
Gillies, Stephen Douglas
Campbell, Jamie Ian
Ali, Mohammed Hanif
Sainson, Richard Charles Alfred
Carvalho, Joana de Abreu
Van Krinks, Cassandra
Sandy, Nikole
Germaschewski, Volker
Lee, E-Chiang
Kirby, Ian
Gallagher, Thomas
Kimber, Rachael Jane
McCourt, Matthew John
Kosmac, Miha
description The present invention relates to antibodies specific for one or more antigens, bispecific antibodies containing one or more domains with specificity to the target(s), and to immunocytokines. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the antibodies, bispecific antibodies and immunocytokines.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title TIGIT antibodies, encoding nucleic acids and methods of using said antibodies in vivo
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