TIGIT antibodies, encoding nucleic acids and methods of using said antibodies in vivo

The present invention relates to antibodies specific for one or more antigens, bispecific antibodies containing one or more domains with specificity to the target(s), and to immunocytokines. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Arkinstall, Stephen John, Gillies, Stephen Douglas, Campbell, Jamie Ian, Ali, Mohammed Hanif, Sainson, Richard Charles Alfred, Carvalho, Joana de Abreu, Van Krinks, Cassandra, Sandy, Nikole, Germaschewski, Volker, Lee, E-Chiang, Kirby, Ian, Gallagher, Thomas, Kimber, Rachael Jane, McCourt, Matthew John, Kosmac, Miha
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to antibodies specific for one or more antigens, bispecific antibodies containing one or more domains with specificity to the target(s), and to immunocytokines. The present invention also provides methods of treatment, uses and pharmaceutical compositions comprising the antibodies, bispecific antibodies and immunocytokines.