Composition containing inducer of SIRT1 expression for preventing or treating sepsis or septic shock

The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by re...

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Bibliographische Detailangaben
Hauptverfasser: Han, Myung Kwan, Song, Eun Kyung, Yoo, Chae Hwa, Lee, Seung Ok
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to a composition containing an inducer of SIRT1 (silent mating type information regulation 2 homolog) expression for preventing or treating sepsis or septic shock. The inducer of SIRT1 expression can remarkably reduce the mortality caused by sepsis or septic shock by reducing pro-inflammatory cytokines and increasing anti-inflammatory cytokines. Therefore, the inducer of SIRT1 expression is useful for preventing or treating sepsis or septic shock.