Sustained-release triptan compositions and method of use the same through subdermal route or the like

Provided is a sustained-release triptan composition as a suitable depot formulation to carry a therapeutically effective amount of triptan for administration via subcutaneous or intramuscular injection. This sustained-release triptan composition is characterized by a high drug to phospholipid ratio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kao, Hao-Wen, Lin, Yi-Yu, Hong, Keelung
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Provided is a sustained-release triptan composition as a suitable depot formulation to carry a therapeutically effective amount of triptan for administration via subcutaneous or intramuscular injection. This sustained-release triptan composition is characterized by a high drug to phospholipid ratio and provides an improved pharmacokinetic profile in vivo. The sustained-release triptan composition is for use as a medicament in the treatment of migraine or cluster headache.