Automated stain finding in pathology bright-field images

Automated stain finding. In an embodiment, an image of a sample comprising one or more stains is received. For each of a plurality of pixels in the image, an optical density vector for the pixel is determined. The optical density vector comprises a value for each of the one or more stains, and repre...

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Bibliographische Detailangaben
Hauptverfasser:	Olson, Allen, Georgescu, Walter, Annaldas, Bharat, Saligrama, Kiran
Format:	Patent
Sprache:	eng
Schlagworte:	CALCULATING COMPUTING COUNTING HANDLING RECORD CARRIERS IMAGE DATA PROCESSING OR GENERATION, IN GENERAL INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS PRESENTATION OF DATA RECOGNITION OF DATA RECORD CARRIERS TESTING
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Beschreibung
Zusammenfassung:	Automated stain finding. In an embodiment, an image of a sample comprising one or more stains is received. For each of a plurality of pixels in the image, an optical density vector for the pixel is determined. The optical density vector comprises a value for each of the one or more stains, and represents a point in an optical density space that has a number of dimensions equal to a number of the one or more stains. The optical density vectors are transformed from the optical density space into a representation in a lower dimensional space. The lower dimensional space has a number of dimensions equal to one less than the number of dimensions of the optical density space. An optical density vector corresponding to each of the one or more stains is identified based on the representation.