5′S-LNA nucleotides and oligonucleotides

The invention relates to a compound of formula (I) wherein R2 and R4 are joined and together form a group, such a -CH2O-. The compound of formula (I) can be used in the manufacture of 5′S-LNA oligonucleotides as antisense drugs.

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Bibliographische Detailangaben
Hauptverfasser:	Duschmalé, Joerg, Saha, Goutam, Shaikh, Juber Abdulhamid, Bleicher, Konrad
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a compound of formula (I) wherein R2 and R4 are joined and together form a group, such a -CH2O-. The compound of formula (I) can be used in the manufacture of 5′S-LNA oligonucleotides as antisense drugs.