System and method for cache management

An information handling system for managing a storage system includes storage for storing profile-based cache policy performance prediction models. The information handling system also includes a storage manager that obtains an input-output profile for a workload hosted by the information handling system during a first period of time; obtains performance metrics for cache policies for the storage system using: the input-output profile, and the profile-based cache policy performance prediction models; obtains a ranking of the cache policies based on the performance metrics; selects a cache policy of the cache policies based on the rankings; and updates operation of a cache of the storage system based on the selected cache policy for a second period of time.