Modulators of stimulator of interferon genes (STING)

Modulators of stimulator of interferon genes (STING)

Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.

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Bibliographische Detailangaben
Hauptverfasser: Romano, Joseph J, Leister, Lara Kathryn, Lan, Yunfeng, Morales-Ramos, Angel I, Schulz, Mark J, Ramanjulu, Joshi M, Qu, Junya, Kang, Jianxing, Mehlmann, John F, Zhou, Huiqiang, Graybill, Todd L, Romeril, Stuart Paul, Fosbenner, David T, King, Bryan W, Mahajan, Mukesh K, Pesiridis, George Scott
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Disclosed are compounds having the formula: (I) wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, R17, Rx, and Ry are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.