Compositions and methods for producing high secreted yields of recombinant proteins

The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include...

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Bibliographische Detailangaben
Hauptverfasser: Stevens, Thomas, Hill, Rena, Pesce, Carlos Gustavo, Kittleson, Joshua
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure relates to methods for producing recombinant proteins, as well as compositions used in and produced by such methods. Specifically, the present disclosure relates to methods for producing high secreted yields of recombinant proteins, and the compositions provided herein include recombinant host cells that comprise polynucleotide sequences encoding proteins operably linked to at least 2 distinct secretion signals.