Split-tip catheter including lateral distal openings

A split-tip catheter for placement within the vasculature of a patient and for use in hemodialysis or other suitable procedures, and methods of use. The split-tip catheter can include a catheter body defining a first lumen and a second lumen, and a split distal region extending from a distal end of the catheter body. The split distal region can include an arterial segment defined by an outer wall enclosing an arterial segment lumen, the arterial segment lumen in fluid communication with the catheter body first lumen, and a venous segment defined by an outer wall enclosing a venous segment lumen, the venous segment lumen in fluid communication with the catheter body second lumen, the venous segment outer wall extending from the catheter body distal end to a distal nose portion. The distal nose portion can taper from a first outer perimeter to a second smaller outer perimeter.