Systems and methods for a scalable de-duplication engine

Disclosed herein are systems and method for de-duplicating blocks of data. In one aspect, an exemplary method comprises receiving a block of data at a de-duplication engine that comprises a first block node and a first page node, wherein the first block node stores a single block descriptor for at least two identical blocks previously received and wherein the first page node stores single instances of identical pages in the at least two identical blocks. The method comprises comparing the received block with the at least two identical blocks. In response to determining that the received block partially matches the at least two identical blocks, the method comprises storing a block descriptor of the received block in a second block node and storing at least one page that matches between the received block and the at least two identical blocks in a second page node of the de-duplication engine.