Benzimidazole derivatives and their uses

The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for man...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Kieffer, Madeleine, Guzman-Perez, Angel, Gao, Hua, Panteleev, Jane, Hua, Zihao, Stellwagen, John, White, Ryan D, Bartberger, Michael D, Lin, Daniel C. H, Weiss, Matthew, Zhao, Wei, Milgram, Benjamin Charles, Schenkel, Laurie, Chakka, Nagasree, Horne, Daniel B
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.