Composition for gene delivery comprising chitosan and liquid crystal formation material

Disclosed herein is a composition for gene delivery which forms into liquid crystals in an aqueous fluid including chitosan and a liquid crystal formation material. The composition of the present invention including chitosan and a liquid crystal formation material improves the relatively low binding...

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Bibliographische Detailangaben
Hauptverfasser: Noh, Sang Myoung, Hwang, Ho Young, Hwang, Ji Hye, Ki, Min Hyo, Lee, Young Nam
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed herein is a composition for gene delivery which forms into liquid crystals in an aqueous fluid including chitosan and a liquid crystal formation material. The composition of the present invention including chitosan and a liquid crystal formation material improves the relatively low binding strength between chitosan and a gene, and also considerably increases the stability of a chitosan nanocomposite in blood serum, thereby performing highly efficient gene delivery and providing excellent stability, thus being useful as a gene therapeutic agent.