Antibody against human DLK1 and use thereof

Antibody against human DLK1 and use thereof

The present invention relates to an antibody against delta-like 1 homolog (Drosophila) (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Si Hyung, Baek, Gi Sun, Choi, Yunseon, Song, Youngja, Cho, Young-Gyu, Lim, Jung Chae, Lee, Sang Pil, Yoo, Seok Ho, Park, Jae Eun, Park, Young Woo, Kim, Yeung chul, Shin, Ji-Young, Yoon, Sunha, Park, Bum-chan, Lee, Jisu
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to an antibody against delta-like 1 homolog (Drosophila) (DLK1) or an antigen-binding fragment thereof, a nucleic acid encoding the same, a vector comprising the nucleic acid, a cell transformed with the vector, a method for producing the antibody or an antigen-binding fragment thereof, an antibody drug conjugate (ADC) comprising the same, a pharmaceutical composition for treating cancer, a composition for diagnosing cancer, and a chimeric antigen receptor (CAR) and a T-cell engager comprising the same.