Industrial process for the synthesis of nomegestrol-acetate

The invention relates to the last step of a synthetic process, in which Nomegestrol-acetate of formula (I) is synthesized from 17α-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution.

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Bibliographische Detailangaben
Hauptverfasser:	Mahó, Sándor, Sánta, Csaba, Balogh, László, Béni, Zoltán, Horváth, János, Csörgei, János, Vincze, Péter
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The invention relates to the last step of a synthetic process, in which Nomegestrol-acetate of formula (I) is synthesized from 17α-acetoxy-6-methylene-19-norpregn-4-ene-3,20-dione of formula (II) in the presence of Pd/C catalyst and acetic acid in hot ethanolic solution.