Method and system for suspension culture

The present invention relates to cell culture in bioreactors, such as flexible cellbag bioreactors. More closely the invention relates to a method and system for determining the cell density in a bioreactor culture and for controlling the perfusion rate of a suspension culture of cells in a bioreact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Janas, Michelle Louise, Dulgar Tulloch, Aaron, Glover, Clive
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to cell culture in bioreactors, such as flexible cellbag bioreactors. More closely the invention relates to a method and system for determining the cell density in a bioreactor culture and for controlling the perfusion rate of a suspension culture of cells in a bioreactor, comprising measuring the oxygen uptake of primary mononuclear cells in a non-static bioreactor.