Compositions and methods for inducing protective immunity against human immunodeficiency virus infection

Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polype...

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Hauptverfasser: Tomaka, Frank, Hendriks, Jennifer Anne, Van Manen, Danielle, Schuitemaker, Johanna, Barouch, Dan, Pau, Maria Grazia
Format: Patent
Sprache:eng
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Zusammenfassung:Compositions, vaccines and methods for inducing an immunity, including a protective immunity, against Human Immunodeficiency Virus (HIV) infection are described. Heterologous vaccine combinations of one or more adenovirus 26 vectors using for priming immunization and an isolated HIV antigenic polypeptide in combination with one or more MVA vectors for boosting immunization induced strong protective immunity against infections by one or multiple clades of HIV.