Substituted xanthines as inhibitors of transient receptor potential cation channel subfamily c, member 5 activity

Substituted xanthines as inhibitors of transient receptor potential cation channel subfamily c, member 5 activity

The present invention relates to compounds of formula Ia process for their manufacture, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment of conditions having an association with TRPC5 containing ion channels. R1, R2, R3, R4 and R5 have meanings give...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Gerlach, Kai
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to compounds of formula Ia process for their manufacture, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment of conditions having an association with TRPC5 containing ion channels. R1, R2, R3, R4 and R5 have meanings given in the description.