Piperidinone formyl peptide 2 receptor and formyl peptide 1 receptor agonists

The disclosure relates to compounds of formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, ch...

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Bibliographische Detailangaben
Hauptverfasser: Shirude, Pravin Sudhakar, Wurtz, Nicholas R, Viet, Andrew Quoc
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The disclosure relates to compounds of formula (I), which are formyl peptide 2 (FPR2) receptor agonists and/or formyl peptide 1 (FPR1) receptor agonists. The disclosure also provides compositions and methods of using the compounds, for example, for the treatment of atherosclerosis, heart failure, chronic obstructive pulmonary disease (COPD), and related diseases.