Sharing network connections to content sources

Features are disclosed for sharing network connections among client devices. A client device may connect to an intermediary system and request content from content provider. The intermediary system may, in addition to opening a connection with the content provider and receiving the content on behalf of the client, create a request profile for the client device regarding likely future content requests. The request profile may be used to assign the client device to network comparing components that have available open network connections to one or more content providers from which the client device is likely to request content. In some cases, a gateway network computing component may route content requests to other network computing components which have available open network connections to content providers hosting requested content. Additionally, the number of active network computing components may be adjusted to increase connection sharing and reuse opportunities.