Fibronectin based scaffold proteins having improved stability

The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relate...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Yihong, Yeung, Bernice, O'Loughlin, John, Camphausen, Ray
Format: Patent
Sprache:eng
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Zusammenfassung:The present application provides fibronectin based scaffold proteins associated with improved stability. The application also relates to stable formulations of fibronectin based scaffold proteins and the use thereof in diagnostic, research and therapeutic applications. The application further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising such polynucleotides.