Substituted imidazo[1,2-a]pyrazines, pyrazolo[1,5-c]pyrimidines, pyrazolo[1,5-a]pyridines, and purines for the treatment of schistosomiasis

The present invention relates to compounds of formula (1a), formula (1b), formula (1c) or formula (1d):or, or a pharmaceutically acceptable salt thereof, which have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such compounds, salt...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bell, Andrew Simon, Gardner, John Mark Francis
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to compounds of formula (1a), formula (1b), formula (1c) or formula (1d):or, or a pharmaceutically acceptable salt thereof, which have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such compounds, salts or solvates and to the use of such compounds as medicaments, in particular in the treatment or prevention of schistosomiasis, also known as bilharzia.