Nitrogen-containing heterocycle and carbocycle derivatives having TrkA inhibitory activity

The present invention provides a compound having TrkA inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein =X is =O or the like, R 5 and R 5A are hydrogen atoms or the like, -A- is -NR 1 - or the like, B i...

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Bibliographische Detailangaben
Hauptverfasser:	Yukimasa, Akira, Fujiu, Motohiro, Nakamura, Kenichiroh, Kano, Kazuya, Yamaguchi, Hiroki
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides a compound having TrkA inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein =X is =O or the like, R 5 and R 5A are hydrogen atoms or the like, -A- is -NR 1 - or the like, B is substituted or unsubstituted aromatic carbocyclyl or the like, R 1 is substituted or unsubstituted alkyl or the like, R 2 is a hydrogen atom or the like, -W-is -CH 2 - or the like, -W A - is -CH 2 - or the like, R 13 is substituted or unsubstituted aromatic carbocyclyl or the like, R 14 is substituted or unsubstituted aromatic heterocyclyl or the like, R 15 is substituted or unsubstituted alkyl or the like, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same.