Thienopyrimidine inhibitors of atypical protein kinase C

The present invention provides a compound of formula (I) or a salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , A, G, M, Q and X are as defined herein. The compound of formula (I) and its salts has aPKC inhibitory activity, and may be used to treat proliferative disorders.

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Bibliographische Detailangaben
Hauptverfasser:	Ott, Gregory R, Roffey, Jonathan R. A, Dorsey, Bruce D, Morris, Emma L, Wagner, Jason C, Soudy, Christelle N, Learn, Keith S
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	The present invention provides a compound of formula (I) or a salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , A, G, M, Q and X are as defined herein. The compound of formula (I) and its salts has aPKC inhibitory activity, and may be used to treat proliferative disorders.