Oil-based adjuvants

The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	Gallo, Guillermo, Foss, Dennis L, Mwangi, Duncan, Dominowski, Paul Joseph, Vora, Shaunak, Mahan, Suman, Rai, Sharath K, Krebs, Richard Lee, Hardham, John Morgan, Mediratta, Sangita, Salmon, Sarah A, Mohr, Kaori, Lightle, Sandra Ann Marie, Wilmes, Lauren
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.