Antibody with non-natural amino acid introduced therein

Antibody with non-natural amino acid introduced therein

The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kimura, Kaname, Ohtake, Kazumasa, Shiraishi, Yasuhisa, Yanagisawa, Tatsuo, Matsumoto, Akiko, Yokoyama, Shigeyuki, Homma, Masakazu, Sakamoto, Kensaku, Kato, Akifumi, Yamaguchi, Yoshimi
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.