Biometric security systems and methods

Exemplary embodiments are directed to a biometric security system including an interface, a biometric acquisition device, and a processing device in communication with the interface and biometric acquisition device. The processing device is configured to display a challenge to a subject via the interface, and receive as input a response to the challenge from the subject. Simultaneous to receiving the response to the challenge from the subject, the processing device is configured to capture a biometric characteristic of the subject with the biometric acquisition device. The processing device is configured to analyze the received response to the challenge relative to a preset valid response, and analyze the captured biometric characteristic of the subject for biometric authenticity. The processing device is configured to verify the subject based on both a successful match between the response to the challenge and the preset valid response, and a successful finding of biometric authenticity.