Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same

Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same

The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The aryl or heteroaryl triazolone derivatives or their pharmaceutically accepta...

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Bibliographische Detailangaben
Hauptverfasser: Ha, Na Ry, Choi, Su Bin, Ju, Mi Kyeong, Kim, Dong Hoon, Han, Tae Dong, Tak, Hee Jae, Kim, Eun Kyung, Park, Sol, Kim, Tae Wang, Jung, Eun Hye, Choi, Hyun Ho
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The aryl or heteroaryl triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).