Endophytes and related methods

The present invention relates to a method for identifying and/or characterising an endophyte strain, said method including providing a plurality of samples of endophytes, subjecting said endophytes to genetic analysis; subjecting said endophytes to metabolic analysis and selecting endophytes having...

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Bibliographische Detailangaben
Hauptverfasser: Rabinovich, Maia Andrea, Kaur, Jatinder, Guthridge, Kathryn Michaela, Ekanayake, Piyumi, Forster, John White, Sawbridge, Timothy Ivor, Spangenberg, German, Rochfort, Simone Jane, Ludlow, Emma Jane Isobel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a method for identifying and/or characterising an endophyte strain, said method including providing a plurality of samples of endophytes, subjecting said endophytes to genetic analysis; subjecting said endophytes to metabolic analysis and selecting endophytes having a desired genetic and metabolic profile. The present invention also relates to novel endophytes having a desired toxin profile wherein the endophyte produces significantly less toxic alkaloids compared with a control endophyte such as standard toxic (ST) endophyte; and/or significantly more alkaloids conferring beneficial properties compared with a control endophyte such as ST endophyte. The present invention also relates to endophyte variants having a desired genetic and metabolic profile, wherein said endophyte variants possess genetic and/or metabolic characteristics that result in a beneficial phenotype in a plant harbouring or otherwise associated with the endophyte variant. Preferably said endophyte variants are generated by polyploidisation or induced chromosome doubling.