Benzoimidazoles as prolyl hydroxylase inhibitors

Benzoimidazoles as prolyl hydroxylase inhibitors

The present invention is directed to benzoimidazole compounds of the formula:and enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful in pharmaceutical compositions and methods for the treatment of disease states, disorde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Venkatesan, Hariharan, Peltier, Hillary M, Phuong, Victor K, Rosen, Mark D, Tarantino, Kyle T, Hocutt, Frances Meredith, Rabinowitz, Michael H, Zhao, Lucy Xiumin, Leonard, Jr., Barry Eastman
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention is directed to benzoimidazole compounds of the formula:and enantiomers, diastereomers, racemates, and pharmaceutically acceptable salts thereof. Compounds of the present invention are useful in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions modulated by prolyl hydroxylase activity.