High density fill and draw fermentation process

The present invention relates to a high cell density fermentation fill and draw process for producing a product in a bioreactor system wherein during the fermentation, medium comprising impurities is removed via the impurity filter unit while new fresh medium is added to the cell culture vessel to r...

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Bibliographische Detailangaben
1. Verfasser: Laustsen, Mads
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to a high cell density fermentation fill and draw process for producing a product in a bioreactor system wherein during the fermentation, medium comprising impurities is removed via the impurity filter unit while new fresh medium is added to the cell culture vessel to replenish consumed nutrients and expelled medium.