Carboxamide derivative and its diastereomers in stable crystalline form

The present disclosure relates to solid crystalline forms of N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3- carboxamide (I) and the diastereomers thereof, and to methods for preparing such crystalline forms. Compound (I)and the diastereomers ther...

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Bibliographische Detailangaben
Hauptverfasser: Heikkinen, Terhi, Törmäkangas, Olli
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure relates to solid crystalline forms of N-((S)-1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3- carboxamide (I) and the diastereomers thereof, and to methods for preparing such crystalline forms. Compound (I)and the diastereomers thereof are potent androgen receptor (AR) modulators useful as a medicament.