Integrated circuit including different types of cells, and method and system of designing the same

A method of generating an integrated circuit design includes receiving input data defining input cells of the integrated circuit design, selecting first standard cells from a first standard cell library to represent the input cells having a first characteristic, selecting second standard cells from a second standard cell library to represent the input cells having a second characteristic different from the first characteristic, and generating output data representing the integrated circuit design by performing placement and routing on the selected first standard cells and the selected second standard cells. The first standard cell library includes a first type of standard cells manufactured using a first diffusion break scheme. The second standard cell library includes a second type of standard cells manufactured using a second diffusion break scheme. Each of the second type of standard cells has a same function as a respective one of the first type of standard cells.