Methods for preparing bis-tetrahydroisoquinoline-containing compounds

(−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.

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Bibliographische Detailangaben
Hauptverfasser: Welin, Eric R, Lapointe, Guillaume, Glibstrup, Emil, Haley, Christopher, Allan, Kevin McCormack, Ngamnithiporn, Aurapat (Fa), Virgil, Scott C, Stoltz, Brian M, Pototschnig, Gerit M, Klatte, Max, Gilmore, Christopher, Gruenanger, Christian, Tadross, Pamela, Negoro, Kenji
Format: Patent
Sprache:eng
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Zusammenfassung:(−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.