System and method for mobile X-ray imaging

A method for X-ray imaging includes determining one or more pre-shot parameters corresponding to a region of interest in a subject based on an optical image of the region of interest obtained from an optical sensor. The method further includes controlling an X-ray device to generate a pre-shot X-ray image using a first X-ray dosage, based on the one or more-pre-shot parameters. The method also includes determining at least one main-shot parameter based on the pre-shot X-ray image. The method includes controlling the X-ray device to generate a main-shot X-ray image using a second X-ray dosage greater than the first X-ray dosage, based on the at least one main-shot parameter.