Sulfonamide derivative having coumarin skeleton
Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2.[Solution]Provided is a sulfonamide derivative having a coum...
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| creator | Inoue, Hidekazu Toki, Tadashi Ota, Masahiro Kawai, Junya Ohki, Hitoshi |
| description | Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2.[Solution]Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents:wherein R, R, R, R, R, Rand Rare the same as defined in the specification,and a salt thereof. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Sulfonamide derivative having coumarin skeleton |
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