Sulfonamide derivative having coumarin skeleton

Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2.[Solution]Provided is a sulfonamide derivative having a coum...

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Bibliographische Detailangaben
Hauptverfasser:	Inoue, Hidekazu, Toki, Tadashi, Ota, Masahiro, Kawai, Junya, Ohki, Hitoshi
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided is a novel compound or a salt thereof inhibiting MTHFD2 and useful for treating a disease caused by overexpression of MTHFD2, a disease involved in overexpression of MTHFD2 and/or a disease associated with overexpression of MTHFD2.[Solution]Provided is a sulfonamide derivative having a coumarin skeleton represented by the following formula (I) and having various substituents:wherein R, R, R, R, R, Rand Rare the same as defined in the specification,and a salt thereof.