Heterogeneous instantiation of high-level language callable library for hardware core

Using a high-level language (HLL) callable library for multiple instances of a core includes detecting, using computer hardware, a reference to an HLL library for a core within an HLL application, determining, using the computer hardware, a plurality of instances of the core by detecting function calls within the HLL application correlated to each of the plurality of instances of the core, and generating, using the computer hardware, interface code within the HLL application for each of the plurality of instances of the core using the HLL library. An executable version of the HLL application is generated, using the computer hardware, wherein the interface code for each of the plurality of instances of the core is bound to the respective instance of the core. The function calls can specify different parameterization files corresponding to the plurality of instances of the core.