GLS1 inhibitors for treating disease
Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided.
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Lewis, Richard Thomas Reyna, Naphtali Han, Michelle Heffernan, Timothy Jones, Philip Hamilton, Matthew Soth, Michael J Petrocchi, Alessia Burke, Jason P |
| description | Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US10738043B2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US10738043B2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US10738043B23</originalsourceid><addsrcrecordid>eNrjZFBx9wk2VMjMy8hMyizJLypWSMsvUigpSk0sycxLV0jJLE5NLE7lYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxocGGBubGFgYmxk5GxsSoAQDhXCaI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>GLS1 inhibitors for treating disease</title><source>esp@cenet</source><creator>Lewis, Richard Thomas ; Reyna, Naphtali ; Han, Michelle ; Heffernan, Timothy ; Jones, Philip ; Hamilton, Matthew ; Soth, Michael J ; Petrocchi, Alessia ; Burke, Jason P</creator><creatorcontrib>Lewis, Richard Thomas ; Reyna, Naphtali ; Han, Michelle ; Heffernan, Timothy ; Jones, Philip ; Hamilton, Matthew ; Soth, Michael J ; Petrocchi, Alessia ; Burke, Jason P</creatorcontrib><description>Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200811&DB=EPODOC&CC=US&NR=10738043B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76418</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20200811&DB=EPODOC&CC=US&NR=10738043B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Lewis, Richard Thomas</creatorcontrib><creatorcontrib>Reyna, Naphtali</creatorcontrib><creatorcontrib>Han, Michelle</creatorcontrib><creatorcontrib>Heffernan, Timothy</creatorcontrib><creatorcontrib>Jones, Philip</creatorcontrib><creatorcontrib>Hamilton, Matthew</creatorcontrib><creatorcontrib>Soth, Michael J</creatorcontrib><creatorcontrib>Petrocchi, Alessia</creatorcontrib><creatorcontrib>Burke, Jason P</creatorcontrib><title>GLS1 inhibitors for treating disease</title><description>Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBx9wk2VMjMy8hMyizJLypWSMsvUigpSk0sycxLV0jJLE5NLE7lYWBNS8wpTuWF0twMim6uIc4euqkF-fGpxQWJyal5qSXxocGGBubGFgYmxk5GxsSoAQDhXCaI</recordid><startdate>20200811</startdate><enddate>20200811</enddate><creator>Lewis, Richard Thomas</creator><creator>Reyna, Naphtali</creator><creator>Han, Michelle</creator><creator>Heffernan, Timothy</creator><creator>Jones, Philip</creator><creator>Hamilton, Matthew</creator><creator>Soth, Michael J</creator><creator>Petrocchi, Alessia</creator><creator>Burke, Jason P</creator><scope>EVB</scope></search><sort><creationdate>20200811</creationdate><title>GLS1 inhibitors for treating disease</title><author>Lewis, Richard Thomas ; Reyna, Naphtali ; Han, Michelle ; Heffernan, Timothy ; Jones, Philip ; Hamilton, Matthew ; Soth, Michael J ; Petrocchi, Alessia ; Burke, Jason P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US10738043B23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Lewis, Richard Thomas</creatorcontrib><creatorcontrib>Reyna, Naphtali</creatorcontrib><creatorcontrib>Han, Michelle</creatorcontrib><creatorcontrib>Heffernan, Timothy</creatorcontrib><creatorcontrib>Jones, Philip</creatorcontrib><creatorcontrib>Hamilton, Matthew</creatorcontrib><creatorcontrib>Soth, Michael J</creatorcontrib><creatorcontrib>Petrocchi, Alessia</creatorcontrib><creatorcontrib>Burke, Jason P</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Lewis, Richard Thomas</au><au>Reyna, Naphtali</au><au>Han, Michelle</au><au>Heffernan, Timothy</au><au>Jones, Philip</au><au>Hamilton, Matthew</au><au>Soth, Michael J</au><au>Petrocchi, Alessia</au><au>Burke, Jason P</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>GLS1 inhibitors for treating disease</title><date>2020-08-11</date><risdate>2020</risdate><abstract>Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US10738043B2 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | GLS1 inhibitors for treating disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T03%3A15%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Lewis,%20Richard%20Thomas&rft.date=2020-08-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS10738043B2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |