GLS1 inhibitors for treating disease

Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided.

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Bibliographische Detailangaben
Hauptverfasser:	Lewis, Richard Thomas, Reyna, Naphtali, Han, Michelle, Heffernan, Timothy, Jones, Philip, Hamilton, Matthew, Soth, Michael J, Petrocchi, Alessia, Burke, Jason P
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I:Methods of inhibition GLS1 activity in a human or animal subject are also provided.