Conjugated polymeric particle and method of making same

A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nona...

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Bibliographische Detailangaben
Hauptverfasser: Thwar, Prasanna Krishnan, Menchen, Steven M, Sokolsky, Tanya, Andruzzi, Luisa, Lui, Alfred, Khan, Shaheer H, Blanchard, Alan, Stolarczyk, Craig, Gremyachinskiy, Dmitriy
Format: Patent
Sprache:eng
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Zusammenfassung:A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.