Compositions and methods for modulating farnesoid X receptors

The present invention relates to compounds of Formula I,a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X rec...

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Hauptverfasser: Roland, Jason Thomas, Tully, David Charles, Chianelli, Donatella, Molteni, Valentina, Rucker, Paul Vincent, Nelson, John, Liu, Xiaodong
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creator Roland, Jason Thomas
Tully, David Charles
Chianelli, Donatella
Molteni, Valentina
Rucker, Paul Vincent
Nelson, John
Liu, Xiaodong
description The present invention relates to compounds of Formula I,a stereoisomer, enantiomer, a pharmaceutically acceptable salt or an amino acid conjugate thereof; wherein variables are as defined herein; and their pharmaceutical compositions, which are useful as modulators of the activity of Farnesoid X receptors (FXR).
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Compositions and methods for modulating farnesoid X receptors
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